Tuesday, February 14, 2017

how does glutathione whiten and brighten the skin?

how does glutathione whiten and brighten the skin?
in addition to keeping our bodies young and health ,glutathione helps to reduce pigmentation in the skin, allowing the skin to appear lighter and brighter. the simplistic explanation of how glutathione works to lighten the skin and reduce hyperpigmentation is that it inhibits an encyme called tyrosinase, which produces melanin, the dark pigment in the skin. the detailed explanation of how glutathione works is as follows:

  • glutathione-induced inhibition of tyrosinase. glycosylation blocks the maturation and transfer of tyrosinase from GERL(golgi-endoplasmic reticulum-lysosome)coated vesicles to the pre-melanosome.
  • direct inactivation of the enzyme tyrosinase by binding and chelating copper within the enzyme's active site.
  • the increase of glutathione-reductase activity in the environment of the melanocytes may stimulate the pigment cells to produce phaelmelanin instead of eumelanin pigment. as expected, the lowest levels of reduced glutathione(GSH) were found associated with eumelanin type pigmentation,whereas the highest ones were gound in the skin with phaeomelanin producing melanocytes.
  • quenching of free radicals and peroxides that contribute to tyrosinase activation and melanin formation.
  • modulation of depigmenting abilities of melanocytotoxic agents.
  • research results also indicate that glutathione inhibits the synthesis and aglutination of melanin by interrupting the function of L-DOPA. since DOPA functions as a cofactor in the monophenolase reaction of tyrosinase, it is proposed that the ratio of 5-S-CD to DOPA may be an important factor in the regulation of tyrosinase activity in situ.
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what is glutathione?

what is glutathione?

glutathione is a tripeptide that is manufactured in our body from three amino acids-cysteine,glutamine and glycine. it is the master anti-oxidant and master detoxifier in the body. it is the most important molecule you need to stay healthy and prevent disease. in addition to providing unparalleled beauty benefits it is the secret to preventing aging,cancer,heart disease, dementia and more, and necessary to treat everything from autism to"alzheimers disease".
glutathione is a critical molecule if we want to stay young, healthy and beautiful-the secret of its power is the sulfur(SH)chemical groups it contains. sulfur is a sticky, smelly molecule. it acts like fly ppaper and all the bad things in the ody stick onto it, including free radicals and toxins like mercury and other heavy mentals.
even though glutathione is manufactured in our bodies, it is depleted by a poor diet, pollution, toxins, medications, stress, trauma, aging, infections and radiation. in addition, many people may be deficient in genes such as GSTM1 that produce enzymes that help recycle glutathione. in short, glutathione deficiency is ubiquitous, and when glutathione becomes depleted we can no longer protect ourselves against free radicals, infections, or cancer and we can not get rid of  toxins. this leads to further sickness and soon we are in the downward spiral of chronic illness.
simply said, we need glutathione to be healthy human beings.




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